Eva Wolf
Principal Investigator
- Project: Project 8.1, Project 8.2
- Research Group
- Address: JGU, Biozentrum II, Hanns-Dieter-Hüsch-Weg 17, 55128 Mainz
- Phone: +49 (0) 6131-39-21701
"Within the RTG we uncovered exciting evolutionary aspects of clock protein structures, their molecular interactions and functions. This shows how proteins are finetuned for optimal performance depending on species and environmental conditions."
- Since 2013: Professor for Structural Biology, Johannes Gutenberg University Mainz (JGU)
- 2014-2024: Adjunct Director, Institute of Molecular Biology (IMB), Mainz
- 2012-2013: Group Leader, Ludwig Maximilan University, Munich
- 2009-2011: Group Leader, Max Planck Institute for Biochemistry, Martinsried
- 2000-2009: Group Leader, Max Planck Institute for Molecular Physiology, Dortmund
- 1996-2000: Postdoctoral Researcher, Rockefeller University, New York
Education:
- 2007: Habilitation in Biochemistry, Ruhr University, Bochum
- 1996: PhD in Biology, European Molecular Biology Laboratory (EMBL), Heidelberg
- 1991: Diploma in Biology, University of Heidelberg
-
Chawla S, O'Neill J, Knight MI, He Y, Wang L, Maronde E, Rodríguez SG, van Ooijen G, Garbarino-Pico E, Wolf E, Dkhissi-Benyahya O, Nikhat A, Chakrabarti S, Youngstedt SD, Zi-Ching Mak N, Provencio I, Oster H, Goel N, Caba M, Oosthuizen M, Duffield GE, Chabot C, Davis SJ (2024)
Timely Questions Emerging in Chronobiology: The Circadian Clock Keeps on Ticking J Circadian Rhythms, 22:2 -
Prorok P, Wolf E, Cardoso MC (2024)
Timeless-Tipin interactions with MCM and RPA mediate DNA replication stress response Front Cell Dev Biol, 12:1346534 -
Vu HH, Behrmann H, Hanić M, Jeyasankar G, Krishnan S, Dannecker D, Hammer C, Gunkel M, Solov’yov IA, Wolf E and Behrmann E (2023)
A marine cryptochrome with an inverse photo-oligomerization mechanism Nature Communications, 14:6918 -
Mat A, Vu HH, Wolf E, Tessmar-Raible K (2023)
All light, everywhere? Photoreceptors at non-conventional sites Physiology (Bethesda), 39(1):30-43 -
Giesecke A, Johnstone PS, Lamaze A, Landskron J, Atay E, Chen KF, Wolf E, Top D, Stanewsky R (2023)
A novel period mutation implicating nuclear export in temperature compensation of the Drosophila circadian clock Curr Biol, 33(2):336-350 -
Zurl M, Poehn B, Rieger D, Krishnan S, Rokvic D , Rajan VBV, Gerrard E , Schlichting M, Orel L, Lucas RJ, Wolf E, Helfrich-Förster C, Raible F and Tessmar-Raible K (2022)
Two light sensors decode moonlight versus sunlight to adjust a plastic circadian/circalunidian clock to moon phase Proc Natl Acad Sci USA, 119(22):e2115725119 -
Daiber A, Frenis K, Kuntic M, Li H, Wolf E, Kilgallen AB, Lecour S, Van Laake LW, Schulz R, Hahad O, Münzel T (2022)
Redox regulatory changes of circadian rhythm by the environmental risk factors traffic noise and air pollution. Antioxid Redox Signal, 37(10-12):679-703 -
Poehn B, Krishnan S, Zurl M, Coric A, Rokvic D, Häfker NS, Jaenicke E, Arboleda E, Orel L, Raible F, Wolf E, Tessmar-Raible K (2022)
A Cryptochrome adopts distinct moon- and sunlight states and functions as sun- versus moonlight interpreter in monthly oscillator entrainment Nature Communications, 13:5220 -
Junglas B, Orru R, Axt A, Siebenaller C, Steinchen W, Heidrich J, Hellmich UA, Hellmann N, Wolf E, Weber SAL and Schneider D (2020)
IM30 IDPs form a membrane-protective carpet upon super-complex disassembly Commun Biol, 3:595 -
Wolf E and Kramer A (2020)
Circadian Regulation: From Molecules to Physiology J Mol Biol, 432:3423–3425 -
Garg A, Orru R, Ye W, Distler U, Chojnacki JE, Köhn M, Tenzer S, Sönnichsen C and Wolf E (2019)
Structural and mechanistic insights into the interaction of the circadian transcription factor BMAL1 with the KIX domain of the CREB-binding protein J Biol Chem, 294:16604–16619 -
Li H, Kilgallen AB, Münzel T, Wolf E, Lecour S, Schulz R, Daiber A and Van Laake LW (2019)
Influence of mental stress and environmental toxins on circadian clocks - implications for redox regulation of the heart and cardioprotection Br J Pharmacol, 177: 5393–5412 -
Schmalen I, Reischl S, Wallach T, Klemz R, Grudziecki A, Prabu JR, Benda C, Kramer A, Wolf E (2014)
Interaction of circadian clock proteins CRY1 and PER2 is modulated by zinc binding and disulfide bond formation Cell, 157(5):1203–1215