Helen May-Simera
Principal Investigator
- Project: Project 9.1, Project 9.2
- Research Group
- Address: imP, Hanns-Dieter-Hüsch-Weg 17 (Biozentrum II, 01.360/01.356), 55128 Mainz
- Phone: +49 6131 39 23575
"Working within the RTG gives us a unique perspective on our research field allowing us to explore connections not previously considered."
- Since 2015: Professor, Institute of Molecular Physiology, Johannes Gutenberg University, Mainz
- 2012-2014: Research Fellow, National Eye Institute, National Institute of Health
- 2008-2011: Postdoctoral Fellow, National Institute of Deafness and Communication Disorders, National Institute of Health
Education:
- 2003-2008: University College London, UK, PhD - Mutational and Functional Analyses of Bardet-Biedl syndrome
- 2003: University of Bath, UK, Master of Biochemistry
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Brücker L, Becker SK, Maißl V, Harms G, Parsons M, May-Simera HL (2023)
The actin-bundling protein Fascin-1 modulates ciliary signalling Journal of Molecular Cell Biology, 15(4), mjad022 -
Ewerling A, Maißl V, Wickstead B, May-Simera HL (2023)
Neofunctionalisation of ciliary BBS proteins to nuclear roles is likely a frequent innovation across eukaryotes iScience, 26(4):106410 -
Volz A, Frei A, Kretschmer V, de Jesus Domingues AM, Ketting RF, Ueffing M, Boldt K, Krämer-Albers E, May-Simera HL (2021)
Bardet-Biedl syndrome proteins modulate the release of bioactive extracellular vesicles Nature Communications, 12(1):5671 -
Eintracht J, Forsythe E, May-Simera HL, Moosajee M (2021)
Translational readthrough of ciliopathy genes BBS2 and ALMS1 restores protein, ciliogenesis and function in patient fibroblasts EBioMedicine, 70:103515 -
Bayer F, Dremova O, Khuu MP, Mammadova K, Pontarollo G, Kiouptsi K, Soshnikova N, May-Simera HL, Endres K and Reinhardt C (2021)
The Interplay between Nutrition, Innate Immunity, and the Commensal Microbiota in Adaptive Intestinal Morphogenesis Nutrients, 13(7):2198 -
Schneider S, De Cegli R, Nagarajan J, Kretschmer V, Matthiessen PA, Intartaglia D, Hotaling N, Ueffing M, Boldt K, Conte I and May-Simera HL (2021)
Loss of Ciliary Gene Bbs8 Results in Physiological Defects in the Retinal Pigment Epithelium Front. Cell Dev. Biol., 9:607121 -
Weißbach S, Sys S, Hewel C, Todorov H, Schweiger S, Winter J, Pfenninger M, Torkamani A, Evans D, Burger J, Everschor-Sitte K,
May-Simera HL and Gerber S (2021)
Reliability of genomic variants across different next-generation sequencing platforms and bioinformatic processing pipelines BMC Genomics, 22(62) -
Brücker L, Kretschmer V and May-Simera HL (2020)
The entangled relationship between cilia and actin. Int J Biochem Cell Biol, 129:105877 -
Kretschmer V and May-Simera HL (2020)
The Role of WNT Signaling During Ciliary-Dependent RPE Development Klin Monbl Augenheilkd, 237:248–258 -
Patnaik SR, Farag A, Brücker L, Volz A, Schneider S, Kretschmer V and May‐Simera HL (2020)
Tissue-dependent differences in Bardet-Biedl syndrome gene expression Biol Cell, 112:39–52