Claudia Keller Valsecchi
Principal Investigator
- Project: Project 17.2, Project A.07
- Research Group
- Address: IMB, Ackermannweg 4, 55128 Mainz
"Nature is by far more complex than the cells and model organisms in the laboratory environment. The gene expression field will learn a lot from looking at gene regulation in natural species in their actual environments."
- Since 2020: Group Leader, Institute of Molecular Biology (IMB), Mainz
- 2013–2020: Postdoctoral Researcher, Max Planck Institute of Immunobiology & Epigenetics, Freiburg
- 2012–2013: Postdoctoral Researcher, Friedrich Miescher Institute (FMI), Basel
Education:
- 2012: PhD in Biochemistry, Friedrich Miescher Institute (FMI), Basel
- 2008: MSc in Molecular Biology, Friedrich Miescher Institute (FMI), Basel
- 2007: BSc in Molecular Biology, Biozentrum, University of Basel
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Basilicata MF, Keller Valsecchi CI (2021)
The good, the bad, and the ugly: Evolutionary and pathological aspects of gene dosage alterations PLOS Genetics, 17(12):e1009906 -
Keller Valsecchi CI, Marois E, Basilicata MF, Georgiev P and Akhtar A (2021)
Distinct mechanisms mediate X chromosome dosage compensation in Anopheles and Drosophila Life Science Alliance, 4(9):e202000996 -
Adrian-Kalchhauser I, Sultan SE, Shama L, Spence-Jones H, Tiso S, Keller Valsecchi CI and Weissing FJ (2021)
Inherited Gene Regulation Unifies Molecular Approaches to Nongenetic Inheritance: Response to Edelaar et al. Trends in Ecology & Evolution, 36(6):477 -
Adrian-Kalchhauser I, Sultan SE, Shama LNS, Spence-Jones H, Tiso S, Keller Valsecchi CI and Weissing FJ (2020)
Understanding 'Non-genetic' Inheritance: Insights from Molecular-Evolutionary Crosstalk Trends Ecol Evol, 35:1078–1089 -
Valsecchi CIK, Basilicata MF, Georgiev P, Gaub A, Seyfferth J, Kulkarni T, Panhale A, Semplicio G, Manjunath V, Holz H, Dasmeh P and Akhtar A (2020)
RNA nucleation by MSL2 induces selective X chromosome compartmentalization Nature, 589:137–142 -
Pessoa Rodrigues C, Herman JS, Herquel B, Valsecchi CIK, Stehle T, Grün D and Akhtar A (2020)
Temporal expression of MOF acetyltransferase primes transcription factor networks for erythroid fate Sci Adv, 6:eaaz4815 -
Renschler G, Richard G, Valsecchi CIK, Toscano S, Arrigoni L, Ramírez F and Akhtar A (2019)
Hi-C guided assemblies reveal conserved regulatory topologies on X and autosomes despite extensive genome shuffling Genes Dev, 33:1591–1612